[化学与生命科学学院]应用化学专业负责人介绍
姓名：欧小文
个人简介：欧小文，女，1990年1月生，2017年获华中科技大学高分子化学与物理专业博士学位，2019年于华中科技大学生命科学与技术学院博士后出站，现任湖北第二师范学院专任教师，副教授（湖二师材料已公示，未发文）。
主讲课程：《蛋白质和酶工程》、《学业指导》、《化学前沿》、《大学生职业生涯规划与就业指导》
研究领域：荧光核酸分子探针的设计及其在分子传感领域中的应用
学术兼职：无
科研成果：
主持科研项目：
国家自然科学基金委员会，青年项目，22004029，基于微纳流控的细胞外囊泡在线分离、标记和超富集检测研究，2021/01-2023/12，30万元，在研。
湖北省教育厅科学技术研究计划项目，青年项目，Q20203003，基于氧化石墨烯-核酸传感的外泌体高效分析研究，2020/01-2021/12，2万元，在研。
研究论文（排名前三）：
1. Ou, X., Liu, Y., Zhang, M., et al. Plasmonic gold nanostructures for biosensing and bioimaging. Microchim. Acta.,2021, 188, 304.
2. Ou, X., Zhan, S., Sun, C., et al. Simultaneous detection of telomerase and miRNA with graphene oxide-based fluorescent aptasensor in living cells and tissue samples. Biosen. Bioelectro., 2019, 124, 199.
3. Ou, X., Hong, F., Zhang, Z., et al. A highly sensitive and facile graphene oxide-based nucleic acid probe: Label-free detection of telomerase activity in cancer patient's urine using AIEgens. Biosen. Bioelectro., 2017, 89, 417.
4. Ou, X., Wei, B., Zhang, Z., et al. Detection of UVA/UVC-induced damage of p53 fragment by rolling circle amplification with AIEgens. Analyst, 2016, 141, 4394.
5. Ou, X., Lou, X., Xia, F., A highly sensitive DNA-AIEgen-based “turn-on” fluorescence chemosensor for amplification analysis of Hg2+ ions in real samples and living cells. Sci. China Chem., 2017, 60, 663.
6. Ou, X., Chen, P., Liu, B., Single-cell analysis with microfluidic devices. Anal.
a) Sci.,2019, 35, 609.
7. Ou, X., Chen, P., Huang, X.,Microfluidic chip electrophoresis for biochemical analysis. J. Sep. Sci., 2020, 43, 258.
8. Sun, C., Ou, X., Cheng, Y., et al.Coordination-induced structural changes of
DNA-based optical and electrochemical sensors for metal ions detection. Dalton Trans., 2019, 48, 5879. (共同一作).
9. Wei, B., Zhang, T., Ou, X., et al. Stereochemistry-guided DNA probe for single nucleotide polymorphisms analysis. ACS Appl. Mater. Interfaces, 2016, 8, 15911.
10. Wei, B., Zhang, T., Ou, X.,et al. Engineering biosensors with dual programmable dynamic ranges. Anal. Chem., 2018, 90, 1506.
11. Liu, N., Yang, Z., Ou, X.,et al. Nanopore-based analysis of biochemical species. Microchim. Acta, 2016, 183, 955.
12. Chen, Y., Sun, C., Ou, X.,et al.Dual-targeted peptide-conjugated multifunctional fluorescent probe with AIEgen for efficient nucleus-specific imaging and long-term tracing of cancer cells, Chem. Sci., 2017, 8, 4571.
学术著作:无
13. 代表性论文：
Ou, X., Zhan, S., Sun, C., et al. Simultaneous detection of telomerase and miRNA with graphene oxide-based fluorescent aptasensor in living cells and tissue samples. Biosen. Bioelectro., 2019, 124, 199.
Ou, X., Hong, F., Zhang, Z., et al. A highly sensitive and facile graphene oxide-based nucleic acid probe: Label-free detection of telomerase activity in cancer patient's urine using AIEgens. Biosen. Bioelectro., 2017, 89, 417.
Ou, X., Wei, B., Zhang, Z., et al. Detection of UVA/UVC-induced damage of p53 fragment by rolling circle amplification with AIEgens. Analyst, 2016, 141, 4394.
获奖情况：
2020年，湖北第二师范学院“科研特别贡献者”；
2021年，“第五届全国生命科学竞赛”省赛二等奖，指导老师；
2021年，湖北第二师范学院“优秀实习指导教师”；